Australianscientistssayanorganiccompound(复合物)usedbyIndianwomentopaintdotsorbindiontheirforeheadscouldholdthekeytoabreakthroughincancertreatment.RoseBengalwasfirstusedintheearly1900sasadyeforfoodtextilesandcosmetics.Butnowitisprovingtobeausefulweaponinthefightagainstskincancer.
Televisionadvertisementsconstantlywarnofthedangersofoverexposuretothefiercesun.Amongthemisthepossibilityofthediseasemelanoma(黑瘤)atypeofskincancer.Morethan1200Australiansdieeveryyearfromthedisease.
InitialtrialsofasolutionofRoseBengalinjectedintosomemelanomacellshavehada75percentsuccessrateincontrollingthedisease.ProfessorJohnThompsonthedirectoroftheMelanomaUnitattheUniversityofSydneysaysthisorganicdyecouldbecomeapowerfulcancer-fightingtreatment.
“Webelieveitworksbygettingintothetumor(肿块)cellsandcausingthemtoself-destruct.Buttheexactmechanismbywhichitworksisnottotallyclear.It’snotusefulforpeoplewhohaveaprimarymelanoma.Thetreatmentofprimarymelanomaissurgicalexcision(切除)”hesaid.“It’susefultoinjecttumorsforpeoplewhohaverecurrences;whentheprimarytreatmenthasfailedandwhenrecurrenceintheareaoratmoredistantsiteshasoccurred.”
About90percentofAustralianswhodevelopmelanomasurvivethankstoearlydiagnosisandtreatment.Ifleftuntreatedhoweverthediseasecanbefatal.
ConvincingyoungerpeopleinAustraliaaboutthedangersofoverexposuretothesunisabattlecampaignersareconstantlywaging.
VeronicaManocka21-year-oldstudenthadtwomajoroperationstoremoveacanceroustumorfromherleg.
“I’vehadalotoffriendswhojustsaid‘IthoughtitwasjustyouknowI’llgetamole(痣)cutoutandthat’sit’whereasIdon’tthinkpeoplerealizehowmuchdangerthey’reputtingthemselvesintoandhoweasyitistostopsomethinglikethishappeningtoyoujustfromdoinglittlethings”saidMarock.
OtherresearchersinAustraliaareinvestigatinggenetictreatmentstoskincancer.Thereisapressingneedforsuchresearchtoproduceeffectivetreatments.Australiansthemajorityofwhomarefair-skinned(浅肤色的)arefourtimesmorelikelytodevelopamelanomathanpeo